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专利概况
专利名称 NOVEL COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF FIBROSIS
申请号 IN201817034940 申请日
公开(公告)号 IN201817034940A 公开(公告)日 2018-09-17
申请(专利权)人 发明人 MAMMOLITI Oscar; JANSEN KOEN KAREL; PALISSE Adeline Marie Elise; JOANNESSE Caroline Martine Andre Marie; MENET Christel Jeanne Marie; ALLART Brigitte; EL BKASSINY Sandy
专利来源 国家知识产权局 转化方式
摘要

The present invention discloses compounds according to Formula I, wherein R1a, R1b, R2a, R2b, R3, R4, R5, R6a, X, Cy1, Cy2, and the subscript n and m are as defined herein. The present invention relates to antagonists compounds of sphingosine 1-phosphate (SIP) receptor, methods for their production, pharmaceutical compositions comprising the same, and methods of treatment using the same, for the prophylaxis and/or treatment of diseases involving fibrotic diseases, inflammatory diseases, autoimmune diseases, metabolic diseases, cardiovascular diseases, and/or proliferative diseases by administering the compound of the invention.

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