The invention relates to medicine, in particular to oncology and can be used for treating multicentric breast cancer.Summary of the invention lies in the fact that are carried out three courses of polychemotherapy with an interval of 28 days, namely Cyclophosphamide 600 mg/m2, Doxorubicin 30 mg/m2 and 5-Fluorouracil 500 mg/m2, which is administered on the 1st and 8th day, then a 0.005% Imunofan solution 1 ml is administered intramuscularly, for 5 days, after 21 days is carried out the radiation therapy with a total dose of 44 Gy, 2 Gy per session, then a 0.005% Imunofan solution 1 ml is repeatedly administered intramuscularly, prior to surgical intervention is taken 200 ml of blood from the patient and centrifuged, afterwards in one recipient is stirred 10 ml of plasma and 10 mg of Methotrexate, and in another recipient is stirred 10 ml of plasma, 10 ml of a mixture of formed elements and 30 mg of Doxorubicin, then the mixtures are incubated at 37癈, for 40 min, during the surgical intervention using methylene blue solution are isolated the lymphatic ducts, then the mixtures from the first recipient are introduced into one of the lymphatic ducts of a large caliber in the proximal direction of the vessel, after which the duct is ligated and incised, radical mastectomy is performed to remove level I, II and III lymph nodes, and tissues adjacent to the removed organ are infiltrated with the mixture from the second recipient.