The invention relates to medicine, in particular to surgery and can be used for treating umbilical hernia in patients with liver cirrhosis.Summary of the method consists in that 24…48 hours before surgical operation from the patient' s blood is separated a suspension of mononuclear cells, containing 3×107 cells/mL and is performed the laparocentesis with the evacuation of 5…8 L of ascitic fluid with intraperitoneal introduction of 2 g of ceftriaxone and 200 mg of ciprofloxacin, also from the patient, 2…3 hours before the operation, are taken 30…40 mL of blood, which is centrifuged for 8…12 min at 3000…3500 rpm to produce a fibrin clot enriched with platelets. It is performed the operation, which consists in that are performed longitudinal or transverse incisions of the skin, subcutaneous tissue and aponeurosis, is mobilized to the cervix and is opened the hernial sac, is introduced its contents into the abdominal cavity and is removed the hernial sac, then is performed the abdominal wall defect plasty by the Sapezhko method with longitudinal duplication or Mayo with transverse duplication. Into the muscle layer around the plasty region, at a distance of 1 cm from its edges is administered the suspension of mononuclear cells, in an amount of 5…15 mL, after which on the performed plasty region is applied the fibrin clot and are sutured the subcutaneous tissue and the skin.