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专利概况
专利名称 RECOMBINANT EL1 PEPTIDE HAVING CYTOTOXIC ACTIVITY RELATIVE TO HUMAN CANCER CELLS
申请号 RU2017142060 申请日
公开(公告)号 RU2683221C1 公开(公告)日
申请(专利权)人 Federalnoe gosudarstvennoe byudzhetnoe uchrezhdenie nauki Institut khimicheskoj biologii i fundamentalnoj meditsiny Sibirskogo otdeleniya Rossijskoj akademii nauk (IKHBFM SO RAN) (RU) 发明人 Koval Olga Aleksandrovna; Volkova Olga Yurevna; Gorchakov Andrej Aleksandrovich; Kulemzin Sergej Viktorovich; Tkachenko Anastasiya Viktorovna; Nushtaeva Anna Andreevna; Kuligina Elena Vladimirovna; Rikhter Vladimir Aleksandrovich; Taranin Aleksandr Vladimirovich
专利来源 国家知识产权局 转化方式
摘要

FIELD : biotechnology.SUBSTANCE : invention relates to biotechnology, specifically to the production of recombinant lactaptine analogues, and can be used in medicine. Plasmid DNA pEL1 is engineered to provide synthesis of a recombinant EL1 peptide in mammalian cells, and the recombinant EL1 peptide having a molecular weight of 14.1?kDa is obtained.EFFECT : invention provides preparing a recombinant anti-tumor EL1 peptide, having high cytotoxic activity relative to human cancer cells.1 cl, 4 dwg, 4 ex

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