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专利概况
专利名称 Alkynyl-substituted heterocyclic compound, preparation method therefor and medical use thereof
申请号 AU2017327954 申请日
公开(公告)号 AU2017327954A1 公开(公告)日
申请(专利权)人 Beijing Innocare Pharma Tech Co Ltd 发明人 Chen Xiangyang; Gao Yingxiang; Kong Norman Xianglong
专利来源 国家知识产权局 转化方式
摘要

The present invention relates to an alkynyl-substituted heterocyclic compound acting as an FGFR inhibitor, a preparation method therefor and the medical use thereof. In particular, the present invention relates to a compound as shown in general formula (I) and a pharmaceutically acceptable salt thereof; a pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof; a method for treating and/or preventing FGFR-associated diseases, particularly tumours, by using the compound or a pharmaceutically acceptable salt thereof; and a preparation method for the compound or a pharmaceutically acceptable salt thereof. The present invention also relates to the use of the compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof in the preparation of a drug for treating and/or preventing FGFR-associated diseases, particularly tumours, wherein the definition of each substituent in general formula (I) is the same as that in the description.

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