专利名称 | Alkynyl-substituted heterocyclic compound, preparation method therefor and medical use thereof | ||
申请号 | AU2017327954 | 申请日 | |
公开(公告)号 | AU2017327954A1 | 公开(公告)日 | |
申请(专利权)人 | Beijing Innocare Pharma Tech Co Ltd | 发明人 | Chen Xiangyang; Gao Yingxiang; Kong Norman Xianglong |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
The present invention relates to an alkynyl-substituted heterocyclic compound acting as an FGFR inhibitor, a preparation method therefor and the medical use thereof. In particular, the present invention relates to a compound as shown in general formula (I) and a pharmaceutically acceptable salt thereof; a pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof; a method for treating and/or preventing FGFR-associated diseases, particularly tumours, by using the compound or a pharmaceutically acceptable salt thereof; and a preparation method for the compound or a pharmaceutically acceptable salt thereof. The present invention also relates to the use of the compound or a pharmaceutically acceptable salt thereof, or the pharmaceutical composition including the compound or a pharmaceutically acceptable salt thereof in the preparation of a drug for treating and/or preventing FGFR-associated diseases, particularly tumours, wherein the definition of each substituent in general formula (I) is the same as that in the description. |