专利 - 详情

专利名称	ANTIFUNGAL SEMI-SYNTHETIC POLYENE ANTIBIOTIC, WATER-SOLUBLE SALTS THEREOF AND PHARMACEUTICAL COMPOSITIONS BASED THEREON
申请号	RU2018112831	申请日
公开（公告）号	RU2688658C1	公开（公告）日
申请（专利权）人	Federalnoe gosudarstvennoe byudzhetnoe nauchnoe uchrezhdenie "Nauchno issledovatelskij institut po izyskaniyu novykh antibiotikov imeni G F Gauze"	发明人	Tevyashova Anna Nikolaevna; Shchekotikhin Andrej Egorovich; Grammatikova Natalya Eduardovna; Bychkova Elena Nikolaevna; Mirchink Elena Pavlovna; Isakova Elena Borisovna; Soloveva Svetlana Evgenevna; Treshchalin Ivan Dmitrievich
专利来源	国家知识产权局	转化方式
摘要	FIELD : chemistry.SUBSTANCE : present invention relates to salts of acetate, L-glutamate, citrate or fumarate of amphotericin B N-(2-aminoethyl)amide of formula I , which can be used in medicine. Pharmaceutical compositions are effective against diseases caused by C. albicans, C. parapsilosis, C. krusei, C. tropicalis, C. glabrata, M. canis, T. Rubrum, Aspergillus.EFFECT : novel antifungal compounds with reduced toxicity and improved stability, pharmaceutical compositions based thereon for treating fungal infections.10 cl, 5 dwg, 2 tbl, 8 ex 1人已参与 0数据匹配