专利名称 | PHOSPHATE AND PHOSPHONATE DERIVATIVES OF 7-AMINO-5-THIO-THIAZOLO[4, 5-D]PYRIMIDINES AND THEIR USE IN TREATING CONDITIONS ASSOCIATED WITH ELEVATED LEVELS OF CX3CR1 AND/OR CX3CL1 | ||
申请号 | WOEP19068169 | 申请日 | |
公开(公告)号 | WO2020008064A1 | 公开(公告)日 | |
申请(专利权)人 | KANCERA AB | 发明人 | V臛BERG Jan; BYSTR諱 Styrbj鰎n; OLSSON Elisabeth; J諲SSON Mattias |
专利来源 | 国家知识产权局 | 转化方式 | |
摘要 |
There is provided a compound of formula (I), wherein R1, R2, Q1 and formula (X) are as defined herein, which compounds are useful in the treatment of diseases and disorders associated with elevated levels of CX3CR1 and/or CX3CL1, in particular acute and/or chronic inflammation, eye diseases, lung diseases, skin diseases, joint and/or bone diseases, autoimmune diseases, cardiovascular diseases, metabolic diseases, brain diseases, neurodegenerative diseases, pain, cancer, liver diseases, kidney diseases, gastrointestinal diseases, human immunodeficiency virus and mood disorders. |