Disclosed is a method of preparing a medical preparation with a carrier based on hyaluronan and/or its derivatives, which can be used in the field of medicine and cosmetics. The medical preparation comprises a conjugate of hyaluronic acid and/or its derivative with a medical substance, according to the general formula A-S—N, where : A is the medical substance; S is the way of linking the medical substance with the carrier; and N is the carrier based on hyaluronic acid and/or its derivatives.