Provided are the uses of a specific antibody, an implantable medical instrument, and a preparation method therefor. The uses are those of a specific antibody of a hematopoietic stem cell marker in preparing a drug for promoting endothelial repair. The surface of the implantable medical instrument is loaded with the specific antibody of hematopoietic stem cell marker. The preparation method comprises loading the specific antibody of the hematopoietic stem cell marker on at least a part of the surface of the implantable medical instrument; and/or binding the specific loaded antibody of the hematopoietic stem cell marker into the hole or the groove of the implantable medical instrument.