Provided are the uses of a specific antibody, an implantable medical instrument, and a preparation method therefor. The uses are those of a specific antibody of an ATP-binding cassette transporter in preparing a drug for promoting endothelial repair. The presenthe surface of the implantable medical instrument is loaded with the specific antibody of the ATP-binding cassette transporter. The preparation method comprises loading the specific antibody of the ATP-binding cassette transporter on at least a part of the surface of the implantable medical instrument; and/or binding the specific loaded antibody of the ATP-binding cassette transporter into the hole or the groove of the implantable medical instrument.