The present invention relates to a novel medical use of a compound according to formula, for the treatment of diseases associated with the secretory of, inflammation state, autoimmune disease, proliferative diseases, allergic, transplant rejection, cartilage turnover with, and / or IL6 or interferon in, the treatment of diseases related to the secretion of interferon. JAK, and in. JAK1 particular I, the compound is also, a pharmaceutical composition. comprising said compound. Disease, autoimmune disease, proliferative diseases with inflammatory conditions by administration and methods for the prevention and, or treatment of diseases associated with hypersecretion of diseases, autoimmune diseases with, allergic, transplant rejection, transplant rejections, and/or interferons, are provided IL6/for the treatment of diseases associated with hypersecretion of interferon.