A traditional Chinese medicine composition, a traditional Chinese medicine compound preparation and a preparation method therefor and the use thereof. The traditional Chinese medicine composition and traditional Chinese medicine compound preparation comprise the following raw materials in parts by weight : 30-60 parts of Smilacis glabrae rhizoma, 10-20 parts of Cinnamomi ramulus, 10-20 parts of Polygonum chinense, and 10-20 parts of Commelinae herba. The preparation method comprises water or ethanol extraction, and concentration to make a lotion, suppository, and gel for preparing an anti-human-papillomavirus drug and drugs for treating and/or preventing vaginitis, cervicitis, and cervical ectopic columnar epithelium.