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专利概况
专利名称 COMPOSITIONS FOR PULMONARY DELIVERY OF LONG-ACTING MUSCARINIC RECEPTOR ANTAGONISTS AND LONG-ACTING B2-ADRENERGIC RECEPTOR AGONISTS AND METHODS AND SYSTEMS ASSOCIATED THEREWITH
申请号 RU2015151358 申请日
公开(公告)号 RU2713404C2 公开(公告)日
申请(专利权)人 ПЕРЛ ТЕРАПЬЮТИКС ИНК; PERL TERAPYUTIKS INK 发明人 ВЕХРИНГ Рейнхард; ВЕХРИНГ РейнхардVEKHRING Rejnkhard; ХАРТМАН Майкл Стивен; ХАРТМАН Майкл СтивенKHARTMAN Majkl Stiven; СМИТ Адриан Эдвард; СМИТ Адриан ЭдвардSMIT Adrian Edvard; ДЖОШИ Видия Б; ДЖОШИ Видия Б DZHOSHI Vidiya B; ДВИВЕДИ Сарваджна Кумар; ДВИВЕДИ Сарваджна КумарDVIVEDI Sarvadzhna Kumar
专利来源 国家知识产权局 转化方式
摘要

FIELD : medicine; pharmaceuticals.SUBSTANCE : group of inventions refers to medicine and pharmacy. Disclosed are : pharmaceutical composition delivered from an inhaler with a measured dose, containing : a suspension medium with a propellant, a plurality of active substance particles comprising a glycopyrrolate or a salt thereof and/or formoterol or a salt thereof, one or more types of respirable suspending particles, each of which is soluble in suspension medium in amount of less than approximately one part per 100 parts of suspension medium, and perforated microstructures, where the total weight of the suspending particles is greater than the total weight of the particles of the active substance, and a method of treating a pulmonary disease or disorder comprising administering the above composition from an inhaler with a measured dose.EFFECT : technical result is providing physical and chemical stability of composition and uniformity of dose delivered by cosuspensions throughout devastation of capacity of inhaler.26 cl, 30 dwg, 14 tbl

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